Stable and Temperature-sensitive Transformation of Rat Kidney Epithelial Cells Suppresses Expression of Acidic Fibroblast Growth Factor 1 but Activates Secretion of Fibroblast Growth Factor 3 (int-2) and Vascular Endothelial Growth Factor1

نویسندگان

  • Alton Jones
  • Guohong Zhang
  • J. Denry Sato
  • Mark T. Herley
  • Hong Liu
  • Takaharu Ichimura
  • Guochen Yan
چکیده

I These studies were supported by USPHS Grants ES05670, DK38639, and cA37589. 2 Present address: Program in Molecular Medicine, University of Massachusells Medical center, 373 Plantation Street, Worcester, MA. 3 Present address: Institute of Biosciences and Technology, Texas A & M University, 2121 West Holcombe Boulevard, Houston, TX. 4 To whom requests for reprints should be addressed, at The W. Alton Jones cell Science center, 10 Old Barn Road, Lake Placid, NY 12946. The abbreviations used are: RPTE, rat kidney proximal tubule epithelial cells; FGF, fibroblast growth factor; VEGF, vascular endothelial growth factor; SV-RPTE, SV4O-transformed RPTE; ts, temperature sensitive; HLJvEc, human cell Growth & Differentiation 349

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تاریخ انتشار 2005